32a Riunione Nazionale
“A. Castellani”
dei Dottorandi di Ricerca in
Discipline Biochimiche
(32nd “A. Castellani” Meeting of PhD students in biochemical sciences)
BRALLO DI PREGOLA (Pavia)
13-16 September 2021
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SCIENTIFIC AND ORGANIZING COMMITTEE
Cesare Balduini
Vittorio Bellotti
Roberta Besio
Ilaria Canobbio
Nazzareno Capitanio
Antonella Forlino
Gianfranco Gilardi
Sofia Giorgetti
Gianni Guidetti
Palma Mangione
Giampaolo Minetti
Giampiero Pietrocola
Marina Porcelli
Sara Raimondi
Antonio Rossi
Annalisa Santucci
Maria Enrica Tira
Mauro Torti
Simona Viglio
SCIENTIFIC AND ORGANIZING SECRETARIAT
Università degli Studi di Pavia
Dipartimento di Biologia e Biotecnologie “Lazzaro Spallanzani”
Laboratori di Biochimica
Via A. Bassi, 21 – 27100 PAVIA
Tel. 0382/987236 – Fax 0382/987240
E-mail: riundott@unipv.it – Homepage: http://www.unipv.it/bralweb
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PROGRAM
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MONDAY, SEPTEMBER 13th, 2021
17.00-20.00 Registration & check-in
20:00 DINNER
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TUESDAY, SEPTEMBER 14th, 2021
8.50-9.00 Opening remarks
Chair: Vittorio Bellotti
9.00-9:50 Prof. ILDIKO SZABO (Padova)
Mitochondrial ion channels: linking biophysics to bioergenetics and pathologies
09.50-10.10 Chiara D’Aprile (Milano)
Effect of a remyelination promoting antibody on the sphingolipid pattern of a microglial cell line
10.10-10.30 Lorenzo Germelli (Pisa)
The 18-kDa translocator protein (TSPO) promotes microglia neurosteroidogenesis to restore CNS homeostasis
COFFEE BREAK
Chair:
11.20-11.40 Ignazio Restivo (Palermo)
Cigarette smoke extract induces eryptosis by death-inducing-signaling-complex (DISC) assembly leading to ceramide formation and p38 MAPK activation
11.40-12.00 Dorina Dobi (Milano)
CFTR modulators and sphingolipids: new insight in the treatment of cystic fibrosis
12.00-12.20 Emma Veronica Carsana (Milano)
GCase-related pathologies and neurodegeneration: plasma membrane and metabolic implications
LUNCH
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Chair:
14.30-15.20 Prof. GENNARO CILIBERTO (Roma/Catanzaro)
Birth, development and glory of genetic vaccines and the seminal contribution of an Italian group
15.20-15.40 Camilla Isgrò (Bari)
Searching for effective inhibitors of the main protease (Mpro) of SARS-CoV-2: an in silico and in vitro study
15.40-16.00 Tania Vanzolini (Urbino)
In vitro activity of Dia-T51, the new humanized monoclonal antibody against β-1,3-glucans of pathogenic fungi
COFFEE BREAK
Chair:
16.00-16.20 Emanuele Criscuolo (Roma)
In silico and in vitro analysis of major cannabis-derived compounds as tools to modulate fatty acid amide hydrolase
16.20-16.40 Marina Fava (Teramo)
Endocannabinoid and pro-resolving lipid mediators act sinergically in primary human macrophages
19:30 DINNER
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21.00-23.00 Serata caminetto:
Ruolo della comunicazione scientifica in una virtuosa relazione
scienza-società
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WEDNESDAY, SEPTEMBER 15th, 2021
Chair:
9.00-10:00 Prof. GIUSEPPE DE NICOLAO (Pavia)
Artificial intelligence for biomedicine: boundaries, horizons, limits
10:00-10.25 Claudia Grillo (Torino)
Directed evolution on cytochrome P450 BM3 A2 mutant
10.25-10.50 Marco Minacori (Roma)
β-hexachlorocyclohexane induces STAT3-mediated chemoresistance in HER2-positive cancer cells
COFFEE BREAK
Chair:
11.20-11.45 Vitale Del Vecchio (Napoli)
β2-AR blockade potentiates ERK/MEK inhibitors effect on HNSCC by regulating Nrf2-mediated defense mechanism
11.45-12.10 Glenda Oliveira (Milano)
Defining the molecular landscape of reparative cardiac cells by MS-imaging and advanced MS-proteomics approaches
12.10-12.35 Eleonora Quartieri (Parma)
NMR metabolic profiling of whole, parotid and submandibular/sublingual saliva for diagnostics purpose
LUNCH
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Chair:
14.30-15.20 Prof. PAOLA CHIARUGI (Firenze)
Tumor metabolic deregulation: lactate and its unconventional role
15.20-15.40 Vanna Denti (Milano)
MALDI-MSI analysis of lipid alterations in FFPE patient-derived breast cancer xenograft for pre-clinical and clinical application
15.40-16.00 Assia Duatti (Firenze)
Stromal lactate promotes prostate cancer aggressiveness by enhancing collagen-dependent cancer cell colonization
COFFEE BREAK
Chair:
16.00-16.20 Francesca Vitiello (Napoli)
Antitumor activity of AdoMet through the modulation of miRNA888-5p in laryngeal carcinoma cells
16.20-16.40 Stefano Zoroddu (Sassari)
Antineoplastic properties of new synthetic molecules
16.40-17.10 Alfredo Smiriglia (Firenze)
Studying the role of estrogens using a human embryonic pluripotent stem cell model of non-alcoholic fatty liver disease
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THURSDAY, SEPTEMBER 16th, 2021
Chair:
9.00-9.50 Prof. ANDREA BELLELLI (Roma)
Thioredoxin reductase: functions, catalytic mechanisms and inhibitors
9.50-10.10 Anastasia Ricci (Urbino)
DDIT4 gene expression is switched on by a new HDAC4 function in ataxia teleangiectasia
10.10-10.30 Maria Rosaria Coppola (Genova)
Development of a zebrafish model for Catel-Manzke disease
10.30 CLOSING REMARKS
COFFEE BREAK AND DEPARTURE
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Web support
Studio Congressi Srl, V.le della Libertà, 17 – 27100 PAVIA
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